Read the full article here:
http://www.ncbi.nlm.nih.gov/pubmed/25516101Tuesday, December 30, 2014
New Methods Discover "Microlesions" in Epileptic Tissue
Researchers have used a novel technique to discover mircolesions
in the brain tissue of epileptic patients, perhaps explaining why seemingly “normal”
regions of the brain can produce seizures. Using genetic analysis coupled with
mathematical modeling, investigators elucidated clusters of genes that act
differently in tissue with high levels of epileptic activity. These genes were
then linked to specific cell types, enabling researchers to predict the types
of neurons and markers present in epileptic tissues. These predictions were
confirmed through histopathology. This novel way to predict cellular abnormalities
through the measurement of genetic composition could be a step towards a better
understanding and more effective treatment of epilepsy
